Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL5311074 | 0.91 | SLC6A9 (0.51) | SLC6A9KDM4EUTS2R | |
| SCHEMBL17280823 | 0.81 | SLC7A5 (0.50) | SLC6A4NOS2MAPTRAB9AATM | |
| SCHEMBL17280836 | 0.80 | SLC7A5 (0.49) | SLC6A4NOS2MAPTRAB9AATM | |
| SCHEMBL685134 | 0.77 | SLC6A4 (0.70) | SLC6A9SLC6A4HRH3HTR2AHRH1 | |
| SCHEMBL8197707 | 0.77 | CYP2D6 (0.64) | SLC6A9SLC6A4HRH3UTS2RHTR2A | |
| SCHEMBL3894545 | 0.77 | CYP2D6 (0.64) | SLC6A9SLC6A4HRH3UTS2RHTR2A | |
| SCHEMBL7053968 | 0.77 | NOS2 (0.44) | SLC6A4NOS2MAPTRAB9AATM | |
| SCHEMBL7582978 | 0.77 | NOS2 (0.56) | SLC6A9SLC6A4HRH3NOS2HTR2A | |
| Maleic Acid SCHEMBL7316880 | 0.76 | SLC6A9 (0.65) | SLC6A9KDM4ENOS2RAB9A | |
| Fumaric Acid SCHEMBL7316884 | 0.76 | SLC6A9 (0.65) | SLC6A9KDM4ENOS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487460-A2 | GLYCURONAMIDES, GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF FLUOXETINE, ANALOGS AND USES THEREOF | A & D Bioscience, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003073988-A2 | GLYCURONAMIDES, GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF FLUOXETINE, ANALOGS AND USES THEREOF | A & D BIOSCIENCE, INC. (US) | 2003-09-12 | — | — | WO | disclosed |