Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569244 | 0.84 | ALDH1A1 (0.34) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL14542891 | 0.84 | ALDH1A1 (0.34) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL7569240 | 0.84 | ALDH1A1 (0.34) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6554890 | 0.83 | ALDH1A1 (0.31) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL7742045 | 0.82 | ALDH1A1 (0.42) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6554562 | 0.82 | ALDH1A1 (0.42) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6554592 | 0.76 | ALDH1A1 (0.37) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6553263 | 0.76 | ALDH1A1 (0.37) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6554596 | 0.76 | ALDH1A1 (0.37) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL6553260 | 0.76 | ALDH1A1 (0.37) | LMNAKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |
| US-6416746-B1 | ULTRAVIOLET RAY AND LIGHT SCREENING MATERIAL GRAFTED TO SILANE, OLIGOSILOXANE, OR POLYSILOXANE WITH IMPROVED SOLUBILITY AND LITTLE PENETRATION; FOR USE IN COSMETICS | ROCHE VITAMINS INC. | 2002-07-09 | — | — | US | disclosed |
| EP-1000950-A2 | Novel indanylidene compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-17 | — | — | EP | disclosed |