Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553226 | 1.00 | PDE4B (0.37) | PDE4BPGRALDH1A1MEN1KMT2A | |
| SCHEMBL301752 | 0.84 | CA1 (0.44) | PGRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16774398 | 0.79 | KDM4E (0.48) | ALDH1A1MAOBKDM4EGAAMAPT | |
| SCHEMBL14428500 | 0.78 | PDE4A (0.41) | PDE4BPGRALDH1A1MEN1KMT2A | |
| SCHEMBL6554596 | 0.75 | ALDH1A1 (0.37) | PDE4BALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6554592 | 0.75 | ALDH1A1 (0.37) | PDE4BALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6553263 | 0.75 | ALDH1A1 (0.37) | PDE4BALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6553260 | 0.75 | ALDH1A1 (0.37) | PDE4BALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4808764 | 0.74 | KDM4E (0.33) | PGRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5397188 | 0.74 | PGR (0.43) | PGRALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |
| US-6416746-B1 | ULTRAVIOLET RAY AND LIGHT SCREENING MATERIAL GRAFTED TO SILANE, OLIGOSILOXANE, OR POLYSILOXANE WITH IMPROVED SOLUBILITY AND LITTLE PENETRATION; FOR USE IN COSMETICS | ROCHE VITAMINS INC. | 2002-07-09 | — | — | US | disclosed |
| EP-1000950-A2 | Novel indanylidene compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-17 | — | — | EP | disclosed |