SCHEMBL6554880

SCHEMBL6554880

C=CCc1ccc(CCBr)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
CYP3A4 P08684 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
XDH P47989 1/20 0.43
GABRA1 P14867 4/20 0.42
GABRB2 P47870 4/20 0.42
CNR2 P34972 4/20 0.42
MEN1 O00255 3/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 3/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
GAA P10253 2/20 0.42
CNR1 P21554 2/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2551764 0.86 ALDH1A1 (0.45) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL6284374 0.85 ALDH1A1 (0.56) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL173301 0.82 ALDH1A1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL1653180 0.80 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL10561330 0.79 TAAR1 (0.48) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Phosphine SCHEMBL28908227 0.79 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Water SCHEMBL29179560 0.79 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Bromide SCHEMBL8645583 0.79 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL2281085 0.79 TDP1 (0.71) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL5500231 0.78 TDP1 (0.50) TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021111992-A1 FLUOROPOLYETHER GROUP-CONTAINING POLYMER, SURFACE TREATMENT AGENT, AND ARTICLE 信越化学工業株式会社 2021-06-10 WO disclosed
EP-1457478-A3 Production of 2-amino-2-[2-(4-alkyl-phenyl)ethyl]propane-1,3-diols Novartis AG (CH) 2004-12-22 EP disclosed
EP-1457478-A2 Production of 2-amino-2-[2-(4-alkyl-phenyl)ethyl]propane-1,3-diols Novartis AG (CH) 2004-09-15 EP disclosed
US-4723018-A USED IN FERROELECTRIC LIQUID CRYSTAL DISPLAYS SEIKO EPSON CORPORATION (JP) 1988-02-02 US disclosed