Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364651 | 0.81 | MAOB (0.40) | TDP1MEN1KMT2ATHRB | |
| SCHEMBL2281085 | 0.81 | TDP1 (0.71) | TDP1MEN1KMT2AHTR2ATAAR1 | |
| SCHEMBL4628332 | 0.79 | TRPA1 (0.46) | — | |
| SCHEMBL6554880 | 0.78 | ALDH1A1 (0.48) | TDP1MEN1KMT2A | |
| SCHEMBL377782 | 0.78 | TDP1 (0.48) | TDP1MEN1KMT2A | |
| SCHEMBL30932186 | 0.78 | TDP1 (0.67) | TDP1MEN1KMT2AHTR2ATAAR1 | |
| SCHEMBL6756868 | 0.78 | TDP1 (0.48) | TDP1MEN1KMT2ATAAR1 | |
| SCHEMBL24197114 | 0.75 | CA2 (0.54) | TDP1ESR1ESR2 | |
| SCHEMBL13269343 | 0.75 | TAAR1 (0.52) | TDP1KMT2AHTR2ATAAR1 | |
| SCHEMBL22265145 | 0.75 | MAOB (0.52) | TDP1HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558747-A4 | GLYCOPROTEIN SYNTHESIS | SCRIPPS RESEARCH INST (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1583816-A4 | PROTEIN ARRAYS | SCRIPPS RESEARCH INST (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1578949-A4 | SITE SPECIFIC INCORPORATION OF KETO AMINO ACIDS INTO PROTEINS | SCRIPPS RESEARCH INST (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1578949-A3 | SITE SPECIFIC INCORPORATION OF KETO AMINO ACIDS INTO PROTEINS | The Scripps Research Institute (US) | 2005-11-10 | — | — | EP | disclosed |
| EP-1583816-A2 | PROTEIN ARRAYS | The Scripps Research Institute (US) | 2005-10-12 | — | — | EP | disclosed |
| EP-1578949-A2 | SITE SPECIFIC INCORPORATION OF KETO AMINO ACIDS INTO PROTEINS | The Scripps Research Institute (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1558747-A2 | GLYCOPROTEIN SYNTHESIS | The Scripps Research Institute (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004058946-A2 | PROTEIN ARRAYS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004035743-A2 | SITE SPECIFIC INCORPORATION OF KETO AMINO ACIDS INTO PROTEINS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004035605-A2 | GLYCOPROTEIN SYNTHESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-04-29 | — | — | WO | disclosed |