⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865708 | 0.74 | — | — | |
| SCHEMBL28202387 | 0.74 | KMT2A (0.34) | — | |
| SCHEMBL298299 | 0.62 | — | — | |
| SCHEMBL18190505 | 0.59 | TPMT (0.37) | — | |
| SCHEMBL27566809 | 0.57 | — | — | |
| SCHEMBL24927971 | 0.56 | — | — | |
| SCHEMBL593548 | 0.53 | MEN1 (0.43) | — | |
| SCHEMBL23611618 | 0.53 | NOTUM (0.33) | — | |
| SCHEMBL31518690 | 0.50 | ALDH1A1 (0.43) | — | |
| P-Xylene SCHEMBL27538150 | 0.48 | ALDH1A1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485396-A2 | NUCLEOSIDE 5'-MONOPHOSPHATE MIMICS AND THEIR PRODRUGS | Biota, Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040023901-A1 | Nucleoside 5'-monophosphate mimics and their prodrugs | BIOTA HOLDINGS LIMITED (AU) | 2004-02-05 | — | — | US | disclosed |
| WO-2003073989-A2 | NUCLEOSIDE 5'-MONOPHOSPHATE MIMICS AND THEIR PRODRUGS | BIOTA, INC. (US) | 2003-09-12 | — | — | WO | disclosed |