Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019288 | 1.00 | HPGD (0.53) | HPGDKDM4EALDH1A1NPSR1MITF | |
| SCHEMBL651502 | 0.88 | L3MBTL1 (0.65) | HPGDKDM4EALDH1A1NPSR1MITF | |
| SCHEMBL24682905 | 0.85 | HPGD (0.58) | HPGDKDM4EALDH1A1NPSR1MAPT | |
| SCHEMBL17471290 | 0.80 | USP2 (0.72) | HPGDALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL24682277 | 0.80 | HPGD (0.64) | HPGDKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL7341322 | 0.79 | CNR2 (0.57) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8260594 | 0.78 | PTGS2 (0.55) | HPGDALDH1A1NPSR1MITFLMNA | |
| SCHEMBL655423 | 0.75 | CNR2 (0.43) | HPGDALDH1A1NPSR1MITFLMNA | |
| SCHEMBL12290141 | 0.74 | HPGD (0.74) | HPGDKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL22610040 | 0.74 | PTGS2 (0.56) | HPGDKDM4EALDH1A1NPSR1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507611-B2 | Crosslinkable polymer material, crosslinked polymer material, and production method thereof | TOYODA GOSEI CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120046418-A1 | CROSSLINKABLE POLYMER MATERIAL, CROSSLINKED POLYMER MATERIAL, AND PRODUCTION METHOD THEREOF | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2012-02-23 | — | — | US | disclosed |