Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836878 | 0.82 | NCEH1 (0.44) | KDM4EPPARGPPARAPPARDPTGS2 | |
| SCHEMBL6930576 | 0.81 | THRA (0.45) | PPARGPPARAPTGS2 | |
| SCHEMBL1836158 | 0.80 | PPARA (0.48) | KDM4EPPARGPPARAPTGS2MCL1 | |
| SCHEMBL1836739 | 0.80 | CXCR5 (0.41) | KDM4EPPARGPPARASLC22A12POLB | |
| SCHEMBL1836104 | 0.79 | PPARA (0.50) | PPARGPPARAPTGS2MCL1 | |
| SCHEMBL1836934 | 0.79 | PPARA (0.50) | PPARGPPARAPTGS2MCL1 | |
| SCHEMBL1837528 | 0.79 | PPARA (0.50) | PPARGPPARAPTGS2MCL1 | |
| SCHEMBL1835054 | 0.79 | PPARA (0.50) | PPARGPPARAPTGS2MCL1 | |
| SCHEMBL1841439 | 0.79 | PPARA (0.50) | PPARGPPARAPTGS2MCL1 | |
| SCHEMBL48020 | 0.77 | SLC22A12 (0.40) | TDP1KDM4EPPARGSLC22A12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | disclosed |