Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930569 | 0.90 | THRA (0.46) | THRATHRBPPARAPPARGMTNR1A | |
| SCHEMBL6557117 | 0.86 | MTNR1A (0.45) | THRATHRBMTNR1AMTNR1BCYP4F2 | |
| SCHEMBL6555053 | 0.81 | TDP1 (0.34) | PPARAPPARGPTGS2 | |
| SCHEMBL728984 | 0.81 | THRA (0.60) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL981970 | 0.79 | THRA (0.67) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL6555051 | 0.78 | CYP4F2 (0.37) | THRATHRBPPARAPPARGMTNR1A | |
| SCHEMBL28511442 | 0.78 | THRA (0.69) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL5682830 | 0.78 | THRA (0.69) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL21681728 | 0.78 | THRA (0.69) | THRATHRBPPARAPPARGLTB4R | |
| SCHEMBL1836583 | 0.78 | THRA (0.69) | THRATHRBPPARAPPARGLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | claimed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | claimed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | claimed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | claimed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | claimed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | disclosed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | disclosed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | disclosed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |