SCHEMBL6555092

SCHEMBL6555092

N#CCCN(CC#N)c1[c]cccc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
USP2 O75604 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DRD3 P35462 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6555084 0.81 MAOB (0.33) ALDH1A1TSHRCYP3A4
SCHEMBL6554156 0.79 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4CYP2C9CYP2C19
SCHEMBL6553712 0.74 MAOB (0.38)
SCHEMBL6555095 0.73 TSHR (0.37) ALDH1A1TSHRUSP2HSD17B10POLB
SCHEMBL22729 0.70
SCHEMBL11793247 0.69 MAOA (0.36) ALDH1A1TSHRCYP3A4USP2
SCHEMBL2290085 0.67 EGFR (0.33)
SCHEMBL816702 0.67 TP53 (0.34) DRD3
SCHEMBL1355931 0.67 MEN1 (0.35) ALDH1A1MEN1KMT2A
SCHEMBL2323987 0.66 USP2 (0.53) ALDH1A1TSHRCYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1234007-B1 OLIGOMERIC METHINE DYES CLARIANT FINANCE BVI LTD (VG) 2004-02-18 EP disclosed
EP-1234007-A1 OLIGOMERIC METHINE DYES Clariant Finance (BVI) Limited (VG) 2002-08-28 EP disclosed
WO-2001036543-A1 OLIGOMERIC METHINE DYES CLARIANT FINANCE (BVI) LIMITED (VG) 2001-05-25 WO disclosed