Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.36 |
| ▸ | PCK1 | P35558 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555287 | 1.00 | ADORA2B (0.56) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6554077 | 0.88 | ADORA2B (0.72) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6554070 | 0.88 | ADORA2B (0.72) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6555301 | 0.85 | ADORA2B (0.60) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6555310 | 0.85 | ADORA2B (0.60) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6553594 | 0.84 | ADORA2B (0.40) | ADORA2BADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL6553611 | 0.84 | ADORA2B (0.59) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6553600 | 0.84 | ADORA2B (0.59) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6555316 | 0.81 | ADORA2B (0.60) | ADORA2BADORA3ADORA2AADORA1PTPN1 | |
| SCHEMBL6555325 | 0.81 | ADORA2B (0.60) | ADORA2BADORA3ADORA2AADORA1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104422-B1 | PHENYL XANTHINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-02-18 | — | — | EP | disclosed |