Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12314793 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8987534 | 0.70 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1 | |
| SCHEMBL15326969 | 0.69 | — | — | |
| SCHEMBL8681557 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1 | |
| SCHEMBL28336817 | 0.69 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL2484051 | 0.68 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL1908110 | 0.67 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1 | |
| SCHEMBL10356048 | 0.66 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL42759 | 0.65 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1 | |
| SCHEMBL43019 | 0.65 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230224-B1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2004-12-29 | — | — | EP | disclosed |
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |