SCHEMBL42759

SCHEMBL42759

COC(C)(C)CC(C)(C)CC(C)(C)OC

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727824 0.90 ALDH1A1 (0.45) ALDH1A1TSHRTDP1
SCHEMBL17952455 0.85 ALDH1A1 (0.41) ALDH1A1TSHRTDP1
SCHEMBL8987534 0.84 ALDH1A1 (0.60) ALDH1A1TSHRTDP1
SCHEMBL16123277 0.81 ALDH1A1 (0.43) ALDH1A1TSHRTDP1
SCHEMBL14968533 0.78 ALDH1A1 (0.48) ALDH1A1TSHRTDP1
SCHEMBL43019 0.77 ALDH1A1 (0.53) ALDH1A1TSHRTDP1
SCHEMBL14904885 0.76 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
SCHEMBL14964157 0.74 ALDH1A1 (0.38) ALDH1A1TSHRTDP1
SCHEMBL9465531 0.74 ALDH1A1 (0.50) ALDH1A1TSHRTDP1
SCHEMBL8681557 0.74 ALDH1A1 (0.50) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US disclosed
US-11274181-B2 Polyimide dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2022-03-15 US disclosed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US disclosed
US-10875946-B2 Polyolefin dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2020-12-29 US disclosed
EP-3684894-A1 POLYIMIDE DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
EP-3684842-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
CN-111133084-A Polyimide dispersants and methods of making and using the same 雪佛龙奥伦耐有限责任公司 2020-05-08 CN disclosed
CN-111094394-A Polyolefin dispersants and methods of making and using the same 雪佛龙奥伦耐有限责任公司 2020-05-01 CN disclosed
WO-2011014665-A2 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-02-03 WO disclosed
US-20110028681-A1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI 2011-02-03 US disclosed
WO-2010117619-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2010-10-14 WO disclosed
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-09-30 US disclosed
US-20100184918-A1 Functionalization of Polyolefins with Phenoxy Derivatives UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-07-22 US disclosed
WO-2010083181-A2 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2010-07-22 WO disclosed
US-5248746-A Cationic polymerization, molecular weight control NIPPON ZEON CO., LTD. (JP) 1993-09-28 US disclosed
EP-0451679-A2 Method of producing polymers NIPPON ZEON CO., LTD. (JP) 1991-10-16 EP disclosed
EP-0397081-A2 Process for preparation of polymer NIPPON ZEON CO., LTD. (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION TERT, TELO2, TSPO ALDH1A1 3744/4885TSHR 279/4885TDP1 451/4885
US-20110028681-A1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS RXFP3, HCAR3, LPAR3 ALDH1A1 2695/4885TSHR 294/4885TDP1 3722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.