Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555567 | 0.93 | PPARA (0.60) | PPARAPPARGPPARDPDE4APDE4B | |
| SCHEMBL6555798 | 0.88 | KDM4E (0.59) | PPARAPPARGPPARDTSHRL3MBTL1 | |
| SCHEMBL6556142 | 0.86 | MEN1 (0.49) | PPARAPPARGPPARDTSHRL3MBTL1 | |
| SCHEMBL6556005 | 0.85 | L3MBTL1 (0.57) | PPARAPPARGPPARDTSHRL3MBTL1 | |
| SCHEMBL6555882 | 0.84 | MEN1 (0.52) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6555809 | 0.84 | PPARA (0.58) | PPARAPPARGPPARDPDE4AL3MBTL1 | |
| SCHEMBL6555917 | 0.83 | ALDH1A1 (0.55) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6556046 | 0.83 | PDE4A (0.47) | PPARAPPARGPPARDPDE4APDE4B | |
| SCHEMBL6555868 | 0.83 | SMN1; SMN2 (0.47) | PPARAPPARGPPARDTSHRL3MBTL1 | |
| SCHEMBL6557264 | 0.82 | KDM4E (0.56) | PPARAPPARGPPARDTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | claimed |