Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 13/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556048 | 0.81 | HSD17B10 (0.58) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL16865132 | 0.78 | MAPT (0.71) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL13052564 | 0.78 | ALDH1A1 (0.42) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL14258999 | 0.77 | MAPT (0.52) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL3191322 | 0.77 | HSD17B10 (0.59) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL14747441 | 0.77 | ALDH1A1 (0.40) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL16183130 | 0.76 | POLB (0.49) | ALDH1A1POLBMEN1HTTKMT2A | |
| Water SCHEMBL1044054 | 0.76 | HSD17B10 (0.58) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL13052549 | 0.74 | ALDH1A1 (0.40) | ALDH1A1POLBMEN1HTTKMT2A | |
| SCHEMBL16800102 | 0.74 | MAPT (0.63) | ALDH1A1POLBMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170117477-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | PPOX, OSTC, OCIAD1 | ALDH1A1 2904/4885POLB 2039/4885MEN1 3348/4885 |
| US-20170117477-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | OCIAD2, OCIAD1, OSTC | ALDH1A1 3182/4885POLB 1126/4885MEN1 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.