Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553212 | 0.68 | PNP (0.41) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL1271646 | 0.64 | CDK1 (0.56) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL4237665 | 0.63 | NOS1 (0.38) | PNPQTRT1NOS1DYRK1AHSD17B10 | |
| Hydrochloric Acid SCHEMBL12474436 | 0.63 | CDK1 (0.54) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL18519933 | 0.61 | NOS1 (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL9054700 | 0.61 | PNP (0.38) | PNPMAPTBLMNOS1KDM4E | |
| SCHEMBL2523525 | 0.60 | NOS1 (0.53) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL6322310 | 0.60 | PNP (0.41) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL3454164 | 0.60 | NOS1 (0.53) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL6055297 | 0.60 | PNP (0.41) | PNPMAPTCDK1CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898575-B1 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT DR (US) | 2004-12-29 | — | — | EP | claimed |