Sugi Predict

Sugi Predict / Compounds / SCHEMBL6556356

SCHEMBL6556356

SCHEMBL6556356

CCOC(=O)C(F)(F)C(=O)[C@H](Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CTRC Q99895 20/20 1.00
▸ CMA1 P23946 18/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6556350 1.00 CTRC (1.00) CTRCCMA1
SCHEMBL6558267 0.91 CTRC (1.00) CTRCCMA1
SCHEMBL6558270 0.91 CTRC (1.00) CTRCCMA1
SCHEMBL8257229 0.90 CTRC (1.00) CTRCCMA1
SCHEMBL6556475 0.89 CTRC (1.00) CTRCCMA1
SCHEMBL6556244 0.87 CTRC (0.77) CTRCCMA1
SCHEMBL6556249 0.87 CTRC (0.77) CTRCCMA1
SCHEMBL6556271 0.86 CTRC (1.00) CTRCCMA1
SCHEMBL6556346 0.86 CTRC (0.84) CTRCCMA1
SCHEMBL6556352 0.85 CTRC (1.00) CTRCCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826671-B1 HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME MITSUBISHI PHARMA CORP (JP) 2004-12-29 — — EP disclosed
US-5948785-A USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. THE GREEN CROSS CORPORATION (JP) 1999-09-07 — — US disclosed
EP-0826671-A1 HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME THE GREEN CROSS CORPORATION (JP) 1998-03-04 — — EP disclosed