SCHEMBL6556244

SCHEMBL6556244

CCOC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(NC(=O)OCc2ccccc2)c1=O

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 10/20 0.77
ELANE P08246 10/20 0.67
CMA1 P23946 8/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6556249 1.00 CTRC (0.77) CTRCELANECMA1
SCHEMBL6558085 0.93 CTRC (0.73) CTRCELANECMA1
SCHEMBL6558089 0.93 CTRC (0.73) CTRCELANECMA1
SCHEMBL6558274 0.92 ELANE (0.77) CTRCELANECMA1
SCHEMBL6556078 0.89 ELANE (0.64) CTRCELANECMA1
SCHEMBL6556076 0.89 ELANE (0.64) CTRCELANECMA1
SCHEMBL8404941 0.89 ELANE (0.64) CTRCELANECMA1
SCHEMBL6557712 0.88 ELANE (0.79) CTRCELANECMA1
SCHEMBL6557691 0.88 ELANE (0.76) CTRCELANECMA1
SCHEMBL6556356 0.87 CTRC (1.00) CTRCCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826671-B1 HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME MITSUBISHI PHARMA CORP (JP) 2004-12-29 EP disclosed
EP-0826671-A1 HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME THE GREEN CROSS CORPORATION (JP) 1998-03-04 EP disclosed