Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116363 | 0.85 | PTGS2 (0.59) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL16014937 | 0.83 | PTGS2 (0.46) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9128778 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9130425 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7906363 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9838070 | 0.83 | ALDH1A1 (0.46) | PTGS2PTGS1ESR1TSHRPGR | |
| Hydrochloric Acid SCHEMBL16014959 | 0.82 | PTGS2 (0.45) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL17464177 | 0.82 | PTGS2 (0.66) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL12896272 | 0.82 | PTGS2 (0.66) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL10774213 | 0.81 | ALDH1A1 (0.43) | PTGS2CXCR1CXCR2LMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414207-B1 | Method for preparing alpha-(-4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO LTD (JP) | 1994-08-03 | — | — | EP | claimed |
| EP-0374850-B1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS CO LTD (JP) | 1994-03-09 | — | — | EP | claimed |
| US-5260477-A | Multistage process of catalytic dehydrogenation and reaction with carbon monoxide then hydrogenation | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-11-09 | — | — | US | claimed |
| EP-0347939-B1 | METHOD FOR PREPARING ALPHA-(4-ISOBUTYLPHENYL) PROPIONIC ACID OR ITS PRECURSOR | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-08-25 | — | — | EP | claimed |
| US-5166419-A | Multistage reaction by catalytic dehydrogenation and reaction with carbon monoxide | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| EP-0414207-A2 | Method for preparing alpha-(-4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1991-02-27 | — | — | EP | claimed |
| EP-0374850-A1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | claimed |
| EP-0347939-A1 | Method for preparing alpha-(4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | claimed |
| EP-1229014-B1 | Purification process for arylcarboxylic acids | ALBEMARLE CORP (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1394141-A1 | Preparation of aryl olefins | ALBEMARLE CORPORATION (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-0961765-B1 | PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES | ALBEMARLE CORP (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-0961763-B1 | PREPARATION OF OLEFINIC COMPOUNDS AND CARBOXYLIC DERIVATIVES THEREOF | ALBEMARLE CORP (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1229014-A1 | Purification process for arylcarboxylic acids | ALBEMARLE CORPORATION (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1095005-A1 | PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES | ALBEMARLE CORPORATION (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0347939-B1 | METHOD FOR PREPARING ALPHA-(4-ISOBUTYLPHENYL) PROPIONIC ACID OR ITS PRECURSOR | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |
| US-5166419-A | Multistage reaction by catalytic dehydrogenation and reaction with carbon monoxide | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5097061-A | From isobutylbenzene and ethylene, dehydrogenation, carboxylation of the p-isobutylstyrene product, catalytic | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| EP-0414207-A2 | Method for preparing alpha-(-4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0374850-A1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0347939-A1 | Method for preparing alpha-(4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |