SCHEMBL655646

SCHEMBL655646

CCCCCc1cccnn1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.57
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.42
FAAH O00519 1/20 0.41
CYP19A1 P11511 6/20 0.41
CYP1A2 P05177 1/20 0.39
MIF P14174 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18596775 0.98 KCNH2 (0.60) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL22308558 0.98 KCNH2 (0.60) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL22307320 0.98 KCNH2 (0.60) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL27678206 0.98 KCNH2 (0.60) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL482984 0.98 KCNH2 (0.60) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL15573512 0.98 KCNH2 (0.60) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL4171814 0.94 KCNH2 (0.48) KCNH2TDP1L3MBTL1CTDSP1FAAH
Piperazine SCHEMBL4836648 0.90 KCNH2 (0.47) KCNH2TDP1L3MBTL1CTDSP1FAAH
SCHEMBL18222818 0.88 FAAH (0.57) KCNH2FAAH
SCHEMBL18222821 0.88 FAAH (0.57) KCNH2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677588-A 2,3,5,5-tetrasubstituted-4-carbonyl imidazole cyclic nitrone compound, preparation method and application 中国科学院成都有机化学有限公司 2023-02-03 CN claimed
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN claimed
CN-115403523-A Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN claimed
CN-115403522-A Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN claimed
EP-1879578-A4 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV PHARMACEUTICAL INC (US) 2009-05-13 EP claimed
EP-2014166-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
EP-2014167-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
EP-2014165-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
EP-2011396-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-07 EP claimed
EP-2011395-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-07 EP claimed
EP-1974608-A1 Arylpyridazines as fungicides Bayer CropScience AG (DE) 2008-10-01 EP claimed
EP-1972623-A1 Arylpyridazines as fungicides Bayer CropScience AG (DE) 2008-09-24 EP claimed
EP-1879578-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV Pharmaceutical Inc. (US) 2008-01-23 EP claimed
WO-2006102029-A9 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV PHARMACEUTICAL INC (US) 2006-12-07 WO claimed
WO-2006102029-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV PHARMACEUTICAL, INC. (US) 2006-09-28 WO claimed
EP-0823657-B1 Silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 2001-05-02 EP claimed
US-5871893-A LEUCO DYE KONICA CORPORATION (JP) 1999-02-16 US claimed
EP-0823657-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1998-02-11 EP claimed
US-5059599-A Anxiolytic agents PIERRE FABRE MEDICAMENT (FR) 1991-10-22 US claimed
EP-0055111-B1 BLACK IMAGE FROM A THERMOGRAPHIC IMAGING SYSTEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-07-23 EP claimed