Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596775 | 1.00 | KCNH2 (0.60) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL27678206 | 1.00 | KCNH2 (0.60) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL15573512 | 1.00 | KCNH2 (0.60) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL22307320 | 1.00 | KCNH2 (0.60) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL482984 | 1.00 | KCNH2 (0.60) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL655646 | 0.98 | KCNH2 (0.57) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL4171814 | 0.92 | KCNH2 (0.48) | KCNH2TDP1L3MBTL1FAAHCYP19A1 | |
| SCHEMBL18222818 | 0.90 | FAAH (0.57) | KCNH2FAAH | |
| SCHEMBL18222821 | 0.90 | FAAH (0.57) | KCNH2FAAH | |
| Piperazine SCHEMBL4836648 | 0.88 | KCNH2 (0.47) | KCNH2TDP1L3MBTL1FAAHCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873288-B2 | Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-16 | — | — | US | disclosed |
| US-11358940-B2 | K-Ras modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210155601-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-05-27 | — | — | US | disclosed |
| US-20200247762-A1 | K-RAS MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247762-A1 | K-RAS MODULATORS | KRAS, HRAS, NRAS | KCNH2 3900/4885TDP1 3974/4885L3MBTL1 1260/4885 |
| US-11358940-B2 | K-Ras modulators | KRAS, HRAS, NRAS | KCNH2 4456/4885TDP1 4647/4885L3MBTL1 3380/4885 |
| US-11873288-B2 | Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) | FAAH, FAAH2, EPHX2 | KCNH2 3416/4885TDP1 3984/4885L3MBTL1 4420/4885 |
| US-20210155601-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | FAAH, FAAH2, EPHX2 | KCNH2 3416/4885TDP1 3984/4885L3MBTL1 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.