Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456355 | 0.81 | PDE7A (0.45) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL4456352 | 0.81 | PDE7A (0.45) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL5878921 | 0.81 | PDE7A (0.61) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL27581742 | 0.80 | PDE7A (0.75) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL2917511 | 0.80 | ALDH1A1 (0.49) | PDE7AHSD17B10LMNAALDH1A1KMT2A | |
| SCHEMBL6556637 | 0.80 | ALDH1A1 (0.49) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL2855080 | 0.78 | ERN1 (0.53) | PDE7AALDH1A1KMT2ATXNRD1TXNRD3 | |
| SCHEMBL4456357 | 0.77 | PDE7A (0.44) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL6815838 | 0.77 | PDE7A (0.56) | PDE7AHSD17B10PDE4BPDE4DPDE7B | |
| SCHEMBL11433378 | 0.76 | PDE7A (0.57) | PDE7ALMNAALDH1A1KMT2ATXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976725-B1 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | claimed |
| US-6077974-A | Process for the continuous preparation of amino-halo-genophenyl alkyl thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | claimed |
| EP-0976725-A2 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | Bayer Aktiengesellschaft (DE) | 2000-02-02 | — | — | EP | claimed |
| EP-0976725-B1 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6077974-A | Process for the continuous preparation of amino-halo-genophenyl alkyl thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | disclosed |
| EP-0976725-A2 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | Bayer Aktiengesellschaft (DE) | 2000-02-02 | — | — | EP | disclosed |