Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557998 | 0.96 | SLC2A1 (0.46) | SLC2A1ALDH1A1GAAKDM4ENISCH | |
| SCHEMBL9657128 | 0.87 | KMT2A (0.44) | SLC2A1ALDH1A1GAAIDO1TDO2 | |
| 2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL41575 | 0.83 | IDO1 (0.55) | ALDH1A1GAAIDO1TDO2IDO2 | |
| SCHEMBL6556711 | 0.83 | CYP1A2 (0.46) | SLC2A1ALDH1A1GAAIDO1TDO2 | |
| SCHEMBL61350 | 0.81 | SLC2A1 (0.61) | SLC2A1ALDH1A1GAAKDM4EMAPT | |
| 2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL29279416 | 0.81 | IDO1 (0.57) | ALDH1A1IDO1TDO2IDO2KDM4E | |
| SCHEMBL7110610 | 0.81 | SLC2A1 (0.61) | SLC2A1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL12221116 | 0.80 | IDO1 (0.46) | ALDH1A1GAAIDO1TDO2IDO2 | |
| SCHEMBL30327071 | 0.79 | ALDH1A1 (0.45) | SLC2A1ALDH1A1GAAKDM4EMAPT | |
| Water SCHEMBL10498815 | 0.79 | SLC2A1 (0.59) | SLC2A1ALDH1A1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |
| JP-2002521430-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100483-A2 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | Abbott Laboratories (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006137-A2 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1100483-A2 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | Abbott Laboratories (US) | 2001-05-23 | — | — | EP | disclosed |
| US-6166013-A | Glucocortiocoid-selective agents | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000006137-A2 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |