SCHEMBL9657128

SCHEMBL9657128

CN(C)c1ccc(C(c2ccccc2)c2ccc(N(C)C)cc2Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
LMNA P02545 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TP53 P04637 1/20 0.44
ATM Q13315 1/20 0.44
MAPT P10636 5/20 0.42
MEN1 O00255 3/20 0.42
SLC2A1 P11166 2/20 0.41
ALDH1A1 P00352 6/20 0.41
GAA P10253 3/20 0.41
KDM4E B2RXH2 1/20 0.40
TDP1 Q9NUW8 4/20 0.38
CYP3A4 P08684 4/20 0.38
MAPK1 P28482 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
TSHR P16473 3/20 0.38
CYP1A2 P05177 1/20 0.38
PHLPP2 Q6ZVD8 1/20 0.38
GPBAR1 Q8TDU6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6556691 0.87 SLC2A1 (0.43) KMT2ASMN1; SMN2LMNAATMMAPT
SCHEMBL6558665 0.83 KMT2A (0.50) KMT2ASMN1; SMN2LMNANPSR1TP53
SCHEMBL6557998 0.83 SLC2A1 (0.46) KMT2ASMN1; SMN2LMNANPSR1ATM
SCHEMBL5555851 0.82 KMT2A (0.47) KMT2ASMN1; SMN2LMNANPSR1TP53
SCHEMBL11672106 0.81 ALDH1A1 (0.43) KMT2ASMN1; SMN2MAPTMEN1SLC2A1
SCHEMBL10690572 0.80 KMT2A (0.45) KMT2ASMN1; SMN2LMNANPSR1TP53
SCHEMBL6557047 0.80 SLC2A1 (0.46) KMT2ASMN1; SMN2LMNANPSR1TP53
SCHEMBL8777757 0.79 CYP3A4 (0.48) KMT2ASMN1; SMN2LMNANPSR1TP53
SCHEMBL30327120 0.79 LMNA (0.40) KMT2ASMN1; SMN2LMNANPSR1TP53
SCHEMBL7110610 0.78 SLC2A1 (0.61) KMT2AMAPTMEN1SLC2A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130291-A HEAT-SENSITIVE RECORDING PAPER OSAKA SEALING PRINTING CO., LTD. (JP) 1992-07-14 US disclosed
EP-0133182-B1 OXIDATION-REDUCTION COLOR PRODUCTION-TYPE HEAT-SENSITIVE RECORDING UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-03-15 EP disclosed
EP-0055847-B1 PRESSURE SENSITIVE RECORDING UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-04-02 EP disclosed
US-4561000-A METHINE-TYPE CHROMOGEN, BENZOQUINONE OXIDIZER, COLOR PRODUCTION SENSITIVITY REGULATOR, SUBSTRATE MITSUI TOATSU CHEMICALS, INC. (JP) 1985-12-24 US disclosed
EP-0058430-B1 DYESTUFF-CONTAINING MICROSCOPIC CAPSULE DISPERSION FOR RECORD MATERIALS MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-12-04 EP disclosed
US-4398753-A METHINE-TYPE DYES AND QUINONE DERIVATIVE IN REDOX SYSTEM FOR CARBON-FREE REPRODUCTION MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1983-08-16 US disclosed
US-4384871-A Dyestuff-containing microscopic capsule dispersion for record materials MITSUI TOATSU CHEMICALS, INC. (JP) 1983-05-24 US disclosed
EP-0058430-A1 Dyestuff-containing microscopic capsule dispersion for record materials MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-08-25 EP disclosed
EP-0055847-A1 Pressure sensitive recording unit MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-07-14 EP disclosed