SCHEMBL6556746

SCHEMBL6556746

[Os].c1ccc(-c2cc3ccc4ncccc4c3nc2-c2ccccc2)cc1.c1ccc(-c2cc3ccc4ncccc4c3nc2-c2ccccc2)cc1.c1ccc(-c2cc3ccc4ncccc4c3nc2-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
CYP3A4 P08684 1/20 0.46
TOP1 P11387 5/20 0.43
PSMB5 P28074 1/20 0.43
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
PIK3CA P42336 1/20 0.40
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP1B1 Q16678 1/20 0.39
ADORA2A P29274 1/20 0.38
NPC1 O15118 2/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
MAPK10 P53779 1/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 1/20 0.37
CCR1 P32246 2/20 0.36
CCR8 P51685 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1076920 0.99 LMNA (0.50) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL28230679 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL28861474 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL456098 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL9860636 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL6016690 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
Hydrochloric Acid SCHEMBL1571752 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL28630554 0.97 LMNA (0.49) LMNACYP3A4TOP1PSMB5KDM4E
SCHEMBL6866086 0.93 LMNA (0.45) LMNACYP3A4TOP1PSMB5KDM4E
Perchlorate SCHEMBL9112333 0.93 LMNA (0.45) LMNACYP3A4TOP1PSMB5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423691-A1 FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS 3M Innovative Properties Company (US) 2004-06-02 EP disclosed
US-6664111-B2 The detector is a solid polymeric matrix, e.g., siloxane, modified by a luminescent platinum group metal phenanthroline chelate complex which is quenchable by oxygen; blood and tissue samples; medical diagnosis; compact; lightweight 3M INNOVATIVE PROPERTIES COMPANY 2003-12-16 US disclosed
US-20030099574-A1 Fluorescence based oxygen sensor systems 3M INNOVATIVE PROPERTIES COMPANY 2003-05-29 US disclosed
WO-2003019179-A1 FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-03-06 WO disclosed