Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 4/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076920 | 0.95 | LMNA (0.50) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL6556746 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL6016690 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL28230679 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| Hydrochloric Acid SCHEMBL1571752 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL28630554 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL456098 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL9860636 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL28861474 | 0.93 | LMNA (0.49) | LMNACYP3A4TOP1PSMB5KDM4E | |
| SCHEMBL9637300 | 0.90 | LMNA (0.43) | LMNACYP3A4TOP1PSMB5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6808939-B2 | LIGAND FOR USE AS TOOL IN DIAGNOSTIC ANALYSIS | IGEN INTERNATIONAL, INC. | 2004-10-26 | — | — | US | disclosed |
| US-20030027357-A1 | ECL labels having improved non-specific binding properties, methods of using and kits containing the same | BIOVERIS CORPORATION | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027357-A1 | ECL labels having improved non-specific binding properties, methods of using and kits containing the same | HLCS, NONO, EBPL | LMNA 1168/4885CYP3A4 3733/4885TOP1 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.