Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557047 | 0.86 | SLC2A1 (0.46) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL6558728 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL6558698 | 0.81 | SLC2A1 (0.41) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL8053600 | 0.81 | SLC2A1 (0.41) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL6556889 | 0.77 | PDE2A (0.42) | ALDH1A1CYP3A4MAPK1TDP1TP53 | |
| SCHEMBL14046263 | 0.77 | ALDH1A1 (0.73) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL6557998 | 0.76 | SLC2A1 (0.46) | ALDH1A1CYP3A4MAPK1TDP1ALOX15 | |
| SCHEMBL30054040 | 0.76 | MAPT (0.68) | ALDH1A1CYP3A4MAPK1TDP1TSHR | |
| SCHEMBL6556764 | 0.76 | MAPT (0.68) | ALDH1A1CYP3A4MAPK1TDP1TSHR | |
| SCHEMBL6654808 | 0.75 | KMT2A (0.47) | ALDH1A1CYP3A4TP53TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |
| US-6166013-A | Glucocortiocoid-selective agents | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |