SCHEMBL6556895

SCHEMBL6556895

CCc1ccccc1C(=O)ON

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.48
ALDH1A1 P00352 8/20 0.46
LMNA P02545 2/20 0.46
HSD17B10 Q99714 3/20 0.46
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
UTS2R Q9UKP6 1/20 0.43
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
CFTR P13569 1/20 0.41
CLCN2 P51788 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28490955 0.98 TSHR (0.47) TSHRALDH1A1LMNAHSD17B10TDP1
SCHEMBL28558946 0.87 ALDH1A1 (0.50) TSHRALDH1A1LMNAHSD17B10TDP1
SCHEMBL15512619 0.84 TSHR (0.49) TSHRALDH1A1LMNAHSD17B10TDP1
SCHEMBL6464901 0.83 TSHR (0.52) TSHRALDH1A1LMNAHSD17B10TDP1
SCHEMBL739158 0.83 TSHR (0.52) TSHRALDH1A1LMNAHSD17B10TDP1
SCHEMBL29028154 0.83 TSHR (0.44) TSHRALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL28249369 0.82 ALDH1A1 (0.51) TSHRALDH1A1LMNAHSD17B10HTT
SCHEMBL1532511 0.82 TSHR (0.50) TSHRALDH1A1LMNAHSD17B10TDP1
SCHEMBL156281 0.82 ALDH1A1 (0.66) TSHRALDH1A1LMNAHSD17B10HTT
SCHEMBL28089169 0.81 TSHR (0.51) TSHRALDH1A1LMNAHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110495410-A A kind of little yellow croaker frozen sperm and Larimichthys crocea hybridizing propagation process ZHEJIANG ACAD AGRICULTURAL SCI 2019-11-26 CN claimed
CN-102869656-B Tetrahydrobenzothiophene compound ASTELLAS PHARMA INC 2014-03-12 CN claimed
CN-102869656-A Tetrahydrobenzothiophene compound ASTELLAS PHARMA INC 2013-01-09 CN claimed
US-20240034970-A1 CELL CULTURE SUBSTRATE AND MANUFACTURING METHOD THEREOF RICOH COMPANY, LTD. (JP) 2024-02-01 US disclosed
CN-106604942-B Polymer and method of making same 株式会社LG化学 2019-11-26 CN disclosed
CN-110495410-A A kind of little yellow croaker frozen sperm and Larimichthys crocea hybridizing propagation process ZHEJIANG ACAD AGRICULTURAL SCI 2019-11-26 CN disclosed
CN-109923450-A Retardation film, elliptically polarizing plate, and display device using the same DIC株式会社 2019-06-21 CN disclosed
CN-109790296-A Polymer composition comprising (methyl) acrylic acid series polymeric compounds SABIC环球技术有限责任公司 2019-05-21 CN disclosed
CN-109111368-A A kind of preparation method of ethyl o-aminobenzoate 王红凯 2019-01-01 CN disclosed
CN-108495892-A Method for producing polyformaldehyde injection molding object SABIC环球技术有限责任公司 2018-09-04 CN disclosed
US-10053523-B2 Supported polymetal olefin polymerization catalyst, preparation method and use thereof EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-08-21 US disclosed
CN-1723193-A Novel polycyclic compounds which modulate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RES & DEV (FR) 2006-01-18 CN disclosed
US-20040171811-A1 Nonhuman pregnane x receptor sequences for use in comparative pharmacology SMITHKLINE BEECHAM CORPORATION 2004-09-02 US disclosed
EP-1392725-A1 NONHUMAN PREGNANE X RECEPTOR SEQUENCES FOR USE IN COMPARATIVE PHARMACOLOGY SmithKline Beecham Corporation (US) 2004-03-03 EP disclosed
CN-1406625-A Liquid preparation for oral administration SS PHARMACEUTICAL CO (JP) 2003-04-02 CN disclosed
WO-2002094865-A1 NONHUMAN PREGNANE X RECEPTOR SEQUENCES FOR USE IN COMPARATIVE PHARMACOLOGY SMITHKLINE BEECHAM CORPORATION (US) 2002-11-28 WO disclosed
CN-1214675-A Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4-tetrahydroquinoline carboxylic acids having retinoid-like biological activity VISION PHARM LP (US) 1999-04-21 CN disclosed
US-4792625-A USING HETEROGENEOUS SYSTEM WITHOUT PHASE TRANSFER CATALYST YISSUM RESEARCH DEVELOPMENT COMPANY (IL) 1988-12-20 US disclosed
US-4387238-A ANTIINFLAMMATORY, HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANTISPASMODIC AGENTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 1983-06-07 US disclosed
US-4132774-A SUNSCREEN AGENTS GAF CORPORATION (US) 1979-01-02 US disclosed