SCHEMBL6556978

SCHEMBL6556978

Cc1cc(C(=O)NC(C(=O)N2CCCC2)c2cccc(C(=N)N)c2)ccc1C(=O)N1CCCC1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.64
F2 P00734 10/20 0.64
PRSS1 P07477 10/20 0.64
MTTP P55157 1/20 0.47
KLRK1 P26718 1/20 0.42
MICA Q29983 1/20 0.42
RAET1L Q5VY80 1/20 0.42
PLG P00747 1/20 0.42
PLAU P00749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7563536 0.99 F10 (0.63) F10F2PRSS1MTTPKLRK1
SCHEMBL7560669 0.92 F10 (0.56) F10F2PRSS1MTTP
Hydrochloric Acid SCHEMBL7558802 0.91 F10 (0.56) F10F2PRSS1MTTP
SCHEMBL7560823 0.90 F10 (0.52) F10F2PRSS1
SCHEMBL2999019 0.89 F10 (0.52) F10F2PRSS1
Hydrochloric Acid SCHEMBL7558630 0.89 F10 (0.51) F10F2PRSS1
SCHEMBL7561266 0.88 F10 (0.50) F10F2PRSS1
Hydrochloric Acid SCHEMBL7558685 0.87 F10 (0.49) F10F2PRSS1
SCHEMBL7558652 0.84 F10 (0.49) F10F2PRSS1
Hydrochloric Acid SCHEMBL6554532 0.83 F10 (0.48) F10F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390357-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co. KG (DE) 2004-02-25 EP claimed
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
WO-2002062778-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-08-15 WO claimed
EP-1390357-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co. KG (DE) 2004-02-25 EP disclosed
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed
WO-2002062778-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151534-A1 Antithrombotic compounds SERPINC1, PF4, F2 F10 35/4885F2 3/4885PRSS1 776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.