Phosphoric Acid

Phosphoric Acid

SCHEMBL6557342

CC(C)c1nc2cncnc2nc1C(C)C.O=P(O)(O)O

nearest known ligand 0.36

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.36
FDPS P14324 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8023101 0.90 PIK3CG (0.38) PIK3CG
SCHEMBL21657798 0.81 PIK3CG (0.36) PIK3CG
SCHEMBL21657921 0.78 PIK3CG (0.36) PIK3CG
SCHEMBL22792590 0.74 PIK3CG (0.33) PIK3CG
SCHEMBL30792962 0.70 PIK3CG (0.35) PIK3CG
SCHEMBL3292267 0.70 PIK3CG (0.47) PIK3CG
SCHEMBL30290978 0.69 PIK3CG (0.41) PIK3CG
SCHEMBL2490862 0.69 PIK3CG (0.41) PIK3CG
Phosphoric Acid SCHEMBL28981554 0.68 FDPS (0.37) PIK3CGFDPS
SCHEMBL1378685 0.68 PIK3CG (0.46) PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0916394-B1 Method of manufacturing modified particles and manufacturing device therefor SHARP KK (JP) 2004-03-10 EP disclosed
US-6194487-B1 EXPOSURE OF PARTICLES TO SUPERSATURATED VAPOR OF MONOMERS, CONDENSATION AND POLYMERIZATION ON THE SURFACE SHARP KABUSHIKI KAISHA (JP) 2001-02-27 US disclosed
EP-0916394-A2 Method of manufacturing modified particles and manufacturing device therefor Sharp Kabushiki Kaisha (JP) 1999-05-19 EP disclosed