Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.36 |
| ▸ | S100A10 | P60903 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549354 | 0.83 | MEN1 (0.39) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL3894071 | 0.82 | HTR2C (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL9557022 | 0.82 | HTR2C (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL3893269 | 0.82 | HTR2C (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL3889754 | 0.82 | HTR2C (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL10546679 | 0.80 | HAO1 (0.46) | MGLLCYP1A2MAPK1 | |
| SCHEMBL3904216 | 0.79 | MAOA (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL3903397 | 0.79 | MAOA (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL3903581 | 0.79 | MAOA (0.56) | HTR2CHTR6MAOAMAOBMCL1 | |
| SCHEMBL3889262 | 0.79 | MAOA (0.56) | HTR2CHTR6MAOAMAOBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392643-A2 | TRISUBSTITUTED-N- (1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL] BENZAMIDES WHICH INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | claimed |
| WO-2002094767-A2 | TRISUBSTITUTED-N-[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL] BENZAMIDES WHICH INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | ABBOTT LABORATORIES (US) | 2002-11-28 | — | — | WO | claimed |
| CN-111491963-B | Method for producing (meth) acrylic composition, coating material containing (meth) acrylic composition, and cured body | 三菱瓦斯化学株式会社 | 2023-04-28 | — | — | CN | disclosed |
| CN-113710750-B | (meth) acrylic composition, coating material containing same, and cured product | 三菱瓦斯化学株式会社 | 2022-07-12 | — | — | CN | disclosed |
| US-20220145118-A1 | (METH)ACRYLIC COMPOSITION, PAINT AND CURING AGENT COMPRISING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-05-12 | — | — | US | disclosed |
| US-11326073-B1 | (meth)acrylic composition, paint and curing agent comprising same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-05-10 | — | — | US | disclosed |
| CN-113710750-A | (meth) acrylic composition, coating material containing same, and cured product | 三菱瓦斯化学株式会社 | 2021-11-26 | — | — | CN | disclosed |
| CN-108603953-B | Light diffusing agent, light diffusing resin composition, and molded article | 三菱瓦斯化学株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-109790366-B | (meth) acrylic copolymer, resin composition, molded article thereof, and method for producing molded article | 三菱瓦斯化学株式会社 | 2021-04-27 | — | — | CN | disclosed |
| CN-108822245-B | (meth) acrylic acid-based copolymer | 三菱瓦斯化学株式会社 | 2021-02-12 | — | — | CN | disclosed |
| CN-111491963-A | Method for producing (meth) acrylic composition, and coating material and cured body containing (meth) acrylic composition | 三菱瓦斯化学株式会社 | 2020-08-04 | — | — | CN | disclosed |
| EP-1392643-A2 | TRISUBSTITUTED-N- (1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL] BENZAMIDES WHICH INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002094767-A2 | TRISUBSTITUTED-N-[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL] BENZAMIDES WHICH INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | ABBOTT LABORATORIES (US) | 2002-11-28 | — | — | WO | disclosed |
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |
| US-4596887-A | Cyclization of straight chain ketone, halogen containing derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4570005-A | REACTING THE ARYL PROPYL CHLORIDE WITH THE CORRESPONDING ARYL ALCOHOL OR ARYL MERCAPTAN | MITSUITOATSU CHEMICALS INC. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4397864-A | LOW TOXICITY | MITSUITOATSU CHEMICALS INC. (JP) | 1983-08-09 | — | — | US | disclosed |
| US-4282249-A | INSECTICIDES, ACARICIDES | SHELL OIL COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4254277-A | PESTICIDES | SHELL OIL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |