SCHEMBL6557422

SCHEMBL6557422

CCCCCCCCCCCCOc1c(Cl)cc(C(=O)O)cc1Cl

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.64
PLAU P00749 1/20 0.64
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
PLA2G4B P0C869 1/20 0.54
THRA P10827 3/20 0.52
THRB P10828 3/20 0.52
RARB P10826 3/20 0.51
S1PR2 O95136 1/20 0.49
S1PR1 P21453 1/20 0.49
S1PR3 Q99500 1/20 0.49
LPAR2 Q9HBW0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12432454 1.00 PLA2G2A (0.64) PLA2G2APLAUTP53TSHRPLA2G4B
SCHEMBL1708361 0.93 PLAU (0.68) PLA2G2APLAUTP53TSHRPLA2G4B
SCHEMBL4891284 0.89 PLA2G2A (0.54) PLA2G2APLAUTP53TSHRPLA2G4B
SCHEMBL12433154 0.89 PLA2G2A (0.55) PLA2G2APLAUPLA2G4BS1PR2S1PR1
SCHEMBL566358 0.88 PLAU (0.70) PLA2G2APLAU
SCHEMBL11346598 0.87 S1PR2 (0.49) PLA2G2APLAUTP53TSHRPLA2G4B
SCHEMBL6559420 0.87 S1PR2 (0.49) PLA2G2APLAUTP53TSHRPLA2G4B
SCHEMBL6558609 0.84 GALK1 (0.51) PLA2G2ATHRATHRBS1PR2S1PR1
SCHEMBL9623323 0.84 PLAU (0.79) PLAUTSHRTHRATHRB
SCHEMBL11350034 0.83 ESR1 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1394606-A1 Photographic element compound and process EASTMAN KODAK COMPANY (US) 2004-03-03 EP disclosed
US-6641990-B1 Photographic films having light sensitive silver halide emulsion layers containing couplers, which react with dye developers to provide yellow, magenta and cyan colors and images EASTMAN KODAK COMPANY 2003-11-04 US disclosed