Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.55 |
| ▸ | RARA | P10276 | 2/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557441 | 0.81 | RARB (0.62) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL10968845 | 0.77 | RARB (0.62) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL9192303 | 0.75 | RARB (0.58) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL10376383 | 0.75 | THRB (0.44) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL9494490 | 0.75 | RARB (0.62) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL9764072 | 0.74 | RARB (0.50) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL5685909 | 0.74 | RARB (0.71) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL8025721 | 0.74 | RARB (0.55) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL6914448 | 0.74 | RARB (0.50) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL9763731 | 0.73 | RARB (0.52) | RARBRARARARGALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223209-B1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223209-A1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |