Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763731 | 0.99 | RARB (0.52) | RARBHSD11B1RARARARGHTR2A | |
| SCHEMBL9763649 | 0.99 | RARB (0.52) | RARBHSD11B1RARARARGHTR2A | |
| SCHEMBL9763632 | 0.99 | RARB (0.52) | RARBHSD11B1RARARARGHTR2A | |
| SCHEMBL9764331 | 0.99 | RARB (0.52) | RARBHSD11B1RARARARGHTR2A | |
| SCHEMBL9764026 | 0.99 | RARB (0.52) | RARBHSD11B1RARARARGHTR2A | |
| SCHEMBL9505504 | 0.96 | HSD11B1 (0.47) | RARBHSD11B1RARARARGPSMB5 | |
| SCHEMBL9763543 | 0.90 | RARB (0.39) | RARBHSD11B1RARARARGPSMB5 | |
| SCHEMBL8095372 | 0.87 | RARB (0.48) | RARBHSD11B1RARARARGHTR2A | |
| SCHEMBL9764364 | 0.86 | TP53 (0.41) | ALDH1A1MAPT | |
| SCHEMBL9225302 | 0.85 | RARB (0.51) | RARBHSD11B1RARARARGHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |