Urethane

Urethane

SCHEMBL6557740

C=C(C)C(=O)N=C=O.CCOC(N)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.54
ALDH1A1 P00352 6/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 3/20 0.35
GAA P10253 2/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
THRB P10828 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 2/20 0.31
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157138 0.80
Urethane SCHEMBL1415077 0.78 ALOX15 (0.71) ALOX15ALDH1A1LMNAHSD17B10TSHR
Fluoride SCHEMBL8839901 0.78
Urethane SCHEMBL728774 0.78 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10TSHR
SCHEMBL8913184 0.77 ALDH1A1 (0.39) ALOX15ALDH1A1LMNAHSD17B10TSHR
Methacrylic Acid SCHEMBL900407 0.77 ALOX15 (0.68) ALOX15ALDH1A1LMNAHSD17B10TSHR
Methacrylic Acid SCHEMBL2062627 0.77 ALOX15 (0.68) ALOX15ALDH1A1LMNAHSD17B10TSHR
Methacrylic Acid SCHEMBL9903977 0.77 ALOX15 (0.68) ALOX15ALDH1A1LMNAHSD17B10TSHR
Methacrylic Acid SCHEMBL403852 0.77 ALOX15 (0.68) ALOX15ALDH1A1LMNAHSD17B10TSHR
Ethylene Glycol SCHEMBL5436848 0.77 TDP1 (0.31) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0952170-B1 Aqueous coating system from UV-curing isocyanate groups containing urethane(meth)acrylisocyanates BAYER MATERIALSCIENCE AG (DE) 2004-12-22 EP disclosed
EP-0952170-A1 Aqueous coating system from UV-curing isocyanate groups containing urethane(meth)acrylisocyanates BAYER AG (DE) 1999-10-27 EP disclosed