Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.55 |
| ▸ | PPARG | P37231 | 11/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555785 | 0.91 | PPARA (0.55) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6556021 | 0.86 | PPARA (0.59) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6952370 | 0.86 | PPARG (0.61) | PPARAPPARGPPARD | |
| SCHEMBL6555882 | 0.85 | MEN1 (0.52) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6556015 | 0.84 | ALDH1A1 (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6557751 | 0.83 | CXCR3 (0.47) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6953483 | 0.81 | PPARG (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6556142 | 0.81 | MEN1 (0.49) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6555767 | 0.80 | PPARG (0.68) | PPARAPPARGPPARD | |
| SCHEMBL6555917 | 0.80 | ALDH1A1 (0.55) | PPARAPPARGPPARDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | disclosed |