Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559970 | 0.89 | KMT2A (0.56) | USP2MMP2AKR1C3PKMALDH1A1 | |
| SCHEMBL17369299 | 0.84 | PKM (0.64) | USP2MMP2LMNAPKMPOLB | |
| SCHEMBL655768 | 0.83 | USP2 (0.76) | USP2LMNAPKMPOLBALDH1A1 | |
| SCHEMBL3690418 | 0.81 | USP2 (0.80) | USP2AKR1C3LMNAPKMPOLB | |
| SCHEMBL165129 | 0.81 | USP2 (0.80) | USP2AKR1C3LMNAPKMPOLB | |
| SCHEMBL78283 | 0.79 | USP2 (0.69) | USP2MMP2PKMPOLBALDH1A1 | |
| SCHEMBL12169347 | 0.79 | PKM (0.65) | USP2MMP2LMNAPKMPOLB | |
| SCHEMBL19348414 | 0.79 | MEN1 (0.57) | USP2MMP2AKR1C3PKMPOLB | |
| SCHEMBL14132273 | 0.79 | MCOLN3 (0.55) | USP2AKR1C3LMNAPKMPOLB | |
| SCHEMBL11306227 | 0.75 | PKM (0.69) | USP2MMP2PKMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436255-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003024924-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-03-27 | — | — | WO | disclosed |