Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557849 | 0.89 | USP2 (0.53) | KMT2AMMP2PKMMEN1AKR1C3 | |
| SCHEMBL265611 | 0.83 | PKM (0.61) | KMT2AMMP2PKMMEN1ALDH1A1 | |
| SCHEMBL11306227 | 0.79 | PKM (0.69) | KMT2AMMP2PKMMEN1USP2 | |
| SCHEMBL2299332 | 0.79 | KMT2A (0.51) | KMT2APKMMEN1AKR1C3USP2 | |
| SCHEMBL20389408 | 0.79 | KMT2A (0.77) | KMT2AMEN1AKR1C3ALDH1A1TSHR | |
| SCHEMBL3637211 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8218091 | 0.77 | PKM (0.54) | KMT2AMMP2PKMMEN1USP2 | |
| SCHEMBL14132273 | 0.76 | MCOLN3 (0.55) | KMT2APKMMEN1AKR1C3USP2 | |
| SCHEMBL78283 | 0.76 | USP2 (0.69) | KMT2AMMP2PKMMEN1USP2 | |
| SCHEMBL655768 | 0.76 | USP2 (0.76) | KMT2APKMMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436255-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003024924-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-03-27 | — | — | WO | disclosed |