Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444521 | 1.00 | HIF1A (0.60) | HIF1APTGS2ALDH1A1LMNAKDM4E | |
| SCHEMBL8163429 | 0.94 | HIF1A (0.57) | HIF1APTGS2ALDH1A1LMNAKDM4E | |
| SCHEMBL13054270 | 0.91 | HIF1A (0.61) | HIF1APTGS2ALDH1A1LMNAPKM | |
| SCHEMBL13148667 | 0.87 | HIF1A (0.46) | HIF1APTGS2ALDH1A1LMNAHPGD | |
| SCHEMBL6557968 | 0.87 | HIF1A (0.53) | HIF1APTGS2ALDH1A1LMNAKDM4E | |
| SCHEMBL8447501 | 0.87 | HIF1A (0.46) | HIF1APTGS2ALDH1A1LMNAKDM4E | |
| SCHEMBL8447507 | 0.87 | HIF1A (0.46) | HIF1APTGS2ALDH1A1LMNAKDM4E | |
| SCHEMBL23972091 | 0.86 | HIF1A (0.67) | HIF1ALMNAHPGDKMT2AHTT | |
| SCHEMBL7558159 | 0.86 | HIF1A (0.67) | HIF1ALMNAPKMHPGDKMT2A | |
| SCHEMBL25603257 | 0.86 | HIF1A (0.58) | HIF1APTGS2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893433-A1 | ALPHA-ALKOXYIMINOBENZYL DERIVATIVES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |