Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 10/20 | 0.73 |
| ▸ | ELANE | P08246 | 10/20 | 0.70 |
| ▸ | CMA1 | P23946 | 8/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558085 | 1.00 | CTRC (0.73) | CTRCELANECMA1 | |
| SCHEMBL6558274 | 0.94 | ELANE (0.77) | CTRCELANECMA1 | |
| SCHEMBL6556249 | 0.93 | CTRC (0.77) | CTRCELANECMA1 | |
| SCHEMBL6556244 | 0.93 | CTRC (0.77) | CTRCELANECMA1 | |
| SCHEMBL6557712 | 0.90 | ELANE (0.79) | CTRCELANECMA1 | |
| SCHEMBL6557691 | 0.90 | ELANE (0.76) | CTRCELANECMA1 | |
| SCHEMBL6556177 | 0.88 | ELANE (0.68) | CTRCELANECMA1 | |
| SCHEMBL6558258 | 0.87 | ELANE (0.79) | CTRCELANECMA1 | |
| SCHEMBL6558330 | 0.87 | ELANE (0.73) | CTRCELANECMA1 | |
| SCHEMBL6556137 | 0.86 | ELANE (0.81) | CTRCELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |