Perflubutane

Perflubutane

SCHEMBL6558288

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=S(=O)(F)OF

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.40
CA1 P00915 2/20 0.39
MMP1 P03956 2/20 0.39
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP8 P22894 2/20 0.39
MMP13 P45452 2/20 0.39
F2 P00734 4/20 0.34
PRSS1 P07477 4/20 0.34
PRSS2 P07478 4/20 0.34
PRSS3 P35030 4/20 0.34
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perflubutane SCHEMBL8585712 0.81 CA2 (0.40) CA2CA1MMP1MMP2MMP9
Perflubutane SCHEMBL73685 0.79 CA2 (0.48) CA2CA1MMP1MMP2MMP9
SCHEMBL570470 0.79
SCHEMBL9498883 0.79
Perflubutane SCHEMBL4450622 0.79 CA2 (0.39) CA2CA1MMP1MMP2MMP9
Perflubutane SCHEMBL10729476 0.79 CA2 (0.39) CA2CA1MMP1MMP2MMP9
SCHEMBL16050747 0.79 CA2 (0.44) CA2CA1MMP1MMP2MMP9
SCHEMBL11215822 0.79
SCHEMBL19690370 0.77 CA2 (0.42) CA2CA1MMP1MMP2MMP9
SCHEMBL7472231 0.77 CA2 (0.37) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189954-B1 RAPIDLY CROSS-LINKING FLUOROPOLYMER BAYER AG (DE) 2004-03-03 EP claimed
EP-1129114-A1 METHOD FOR PRODUCING A FAST CROSSLINKABLE FLUORORUBBER BAYER AG (DE) 2001-09-05 EP claimed
WO-2000018811-A1 METHOD FOR PRODUCING A FAST CROSSLINKABLE FLUORORUBBER BAYER AKTIENGESELLSCHAFT (DE) 2000-04-06 WO claimed
EP-1189954-B1 RAPIDLY CROSS-LINKING FLUOROPOLYMER BAYER AG (DE) 2004-03-03 EP disclosed
EP-1189954-A1 RAPIDLY CROSS-LINKING FLUOROPOLYMER Bayer Aktiengesellschaft (DE) 2002-03-27 EP disclosed
EP-1129114-A1 METHOD FOR PRODUCING A FAST CROSSLINKABLE FLUORORUBBER BAYER AG (DE) 2001-09-05 EP disclosed
EP-1124894-A1 FLUORORUBBER MIXTURES MADE FAST CROSSLINKABLE FLUORORUBBERS BAYER AG (DE) 2001-08-22 EP disclosed
EP-0908475-B1 Process for the preparation of low viscosity fluoroelastomers BAYER AG (DE) 2001-03-14 EP disclosed
WO-2000073360-A1 RAPIDLY CROSS-LINKING FLUOROPOLYMER BAYER AKTIENGESELLSCHAFT (DE) 2000-12-07 WO disclosed
WO-2000018811-A1 METHOD FOR PRODUCING A FAST CROSSLINKABLE FLUORORUBBER BAYER AKTIENGESELLSCHAFT (DE) 2000-04-06 WO disclosed
WO-2000018832-A1 FLUORORUBBER MIXTURES MADE FAST CROSSLINKABLE FLUORORUBBERS BAYER AKTIENGESELLSCHAFT (DE) 2000-04-06 WO disclosed
EP-0908475-A2 Process for the preparation of low viscosity fluoroelastomers BAYER AG (DE) 1999-04-14 EP disclosed