Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 4/20 | 0.34 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558509 | 1.00 | METAP2 (0.44) | METAP2METAP1MMP2MMP3ITGB3 | |
| Hydrochloric Acid SCHEMBL6559352 | 0.92 | METAP2 (0.44) | METAP2METAP1MMP2MMP3ITGB3 | |
| Hydrochloric Acid SCHEMBL6559362 | 0.92 | METAP2 (0.44) | METAP2METAP1MMP2MMP3ITGB3 | |
| SCHEMBL6560877 | 0.91 | METAP2 (0.47) | METAP2METAP1MMP2MMP3ITGB3 | |
| SCHEMBL6559295 | 0.88 | METAP2 (0.47) | METAP2METAP1MMP3ITGB3ITGA2B | |
| SCHEMBL6558578 | 0.88 | METAP2 (0.44) | METAP2METAP1MMP2MMP3ITGB3 | |
| SCHEMBL6558573 | 0.88 | METAP2 (0.44) | METAP2METAP1MMP2MMP3ITGB3 | |
| Hydrochloric Acid SCHEMBL6558826 | 0.88 | METAP2 (0.45) | METAP2METAP1MMP3ITGB3ITGA2B | |
| SCHEMBL6559017 | 0.88 | METAP2 (0.47) | METAP2METAP1MMP2MMP3GPR88 | |
| SCHEMBL7741760 | 0.88 | METAP2 (0.47) | METAP2METAP1MMP2MMP3GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |