Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 9/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559500 | 0.91 | NPSR1 (0.38) | KCNE1KCNQ1MEN1KMT2AKCNA5 | |
| SCHEMBL6558710 | 0.89 | KCNA5 (0.35) | KCNE1KCNQ1MEN1KMT2AKCNA5 | |
| SCHEMBL6559927 | 0.87 | KCNA5 (0.41) | KCNE1KCNQ1MEN1KMT2AKCNA5 | |
| SCHEMBL6558501 | 0.85 | KCNE1 (0.45) | KCNE1KCNQ1MEN1KMT2AKCNA5 | |
| SCHEMBL6559544 | 0.82 | KCNA5 (0.36) | KCNE1KCNQ1KCNA5NPSR1TBXA2R | |
| SCHEMBL7826231 | 0.82 | KCNE1 (0.36) | KCNE1KCNQ1MEN1KMT2AKCNA5 | |
| SCHEMBL6560833 | 0.82 | KCNE1 (0.50) | KCNE1KCNQ1MEN1KMT2ACYP1A2 | |
| SCHEMBL6558072 | 0.81 | SIRT2 (0.33) | KCNE1KCNQ1MEN1KMT2ACYP1A2 | |
| SCHEMBL6559607 | 0.80 | KCNE1 (0.47) | KCNE1KCNQ1MEN1KMT2AKCNA5 | |
| SCHEMBL6559205 | 0.79 | SMN1; SMN2 (0.38) | KCNE1KCNQ1MEN1KMT2AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |