Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558585 | 0.90 | ESR1 (0.45) | PTGS2ESR1ESR2KDM4ERAB9A | |
| SCHEMBL8172593 | 0.83 | ESR1 (0.44) | PTGS2ESR1ESR2KDM4ERAB9A | |
| SCHEMBL7219386 | 0.76 | MAPT (0.46) | PTGS2TP53KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6948407 | 0.76 | MAOA (0.40) | ESR1ESR2TP53KDM4ERAB9A | |
| SCHEMBL7098191 | 0.74 | MAOA (0.41) | KDM4EMAOAMAOBGAAALDH1A1 | |
| SCHEMBL810958 | 0.73 | CYP17A1 (0.41) | ESR1ESR2KDM4EMAOAMAOB | |
| SCHEMBL9883927 | 0.73 | CNR2 (0.39) | PTGS2MAPTABCB1ACHEBACE1 | |
| SCHEMBL6560778 | 0.71 | MAOA (0.40) | ESR1ESR2KDM4ERAB9ANPC1 | |
| SCHEMBL6208131 | 0.71 | CYP17A1 (0.39) | KDM4EMAOAMAOB | |
| SCHEMBL8476247 | 0.66 | CSNK2A2 (0.46) | PTGS2TP53KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123003-B1 | UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1119559-B1 | 3-PHENYL-PYRONES | BAYER CROPSCIENCE AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6472350-B1 | Utilization of 3-phenyl-pyrones for pest control | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
| US-6441030-B1 | PESTICIDES, FUNGICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| EP-1123003-A1 | UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL | Bayer Aktiengesellschaft (DE) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024256-A1 | UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-04 | — | — | WO | disclosed |