Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558583 | 0.90 | PTGS2 (0.39) | ESR1ESR2PTGS2ABCB1KDM4E | |
| SCHEMBL8172593 | 0.87 | ESR1 (0.44) | ESR1ESR2PTGS2ABCB1PDE3B | |
| SCHEMBL6560778 | 0.80 | MAOA (0.40) | ESR1ESR2KDM4EALDH1A1GAA | |
| SCHEMBL9883927 | 0.77 | CNR2 (0.39) | PTGS2ABCB1MEN1ALDH1A1POLB | |
| SCHEMBL6208131 | 0.70 | CYP17A1 (0.39) | KDM4ECYP1A2 | |
| SCHEMBL7219386 | 0.69 | MAPT (0.46) | PTGS2KDM4EALDH1A1POLBGAA | |
| SCHEMBL3748937 | 0.67 | PDE3B (0.46) | ESR1ESR2PTGS2PDE3BPDE3A | |
| SCHEMBL6948407 | 0.65 | MAOA (0.40) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL8849972 | 0.65 | ABCB1 (0.51) | PTGS2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL11693574 | 0.65 | ESR2 (0.55) | ESR1ESR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123003-B1 | UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6472350-B1 | Utilization of 3-phenyl-pyrones for pest control | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
| EP-1123003-A1 | UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL | Bayer Aktiengesellschaft (DE) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024256-A1 | UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-04 | — | — | WO | disclosed |