SCHEMBL6558595

SCHEMBL6558595

O=C(O)c1cc(Nc2ccccc2Cl)c(C(=O)O)cc1Nc1ccccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.58
TTR P02766 2/20 0.57
MAPT P10636 2/20 0.57
AKR1C3 P42330 2/20 0.57
CYP1A2 P05177 2/20 0.57
HPGD P15428 2/20 0.57
CYP2C19 P33261 2/20 0.57
MEN1 O00255 1/20 0.57
USP2 O75604 1/20 0.57
MT-CO2 P00403 1/20 0.57
LMNA P02545 1/20 0.57
PLA2G1B P04054 1/20 0.57
PGR P06401 1/20 0.57
CYP3A4 P08684 1/20 0.57
HTR1A P08908 1/20 0.57
ADRA2A P08913 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
AR P10275 1/20 0.57
CYP2C9 P11712 1/20 0.57
HTR2A P28223 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30832916 1.00 PBRM1 (0.58) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL14598922 0.93 MAPT (0.61) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL4249088 0.87 PBRM1 (0.75) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL30575470 0.87 PBRM1 (0.75) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL14576292 0.86 GRIK1 (0.73) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL30611313 0.86 GRIK1 (0.73) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL28297347 0.85 PBRM1 (0.73) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL27404918 0.85 AKR1C3 (0.61) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL4216661 0.84 FTO (0.58) PBRM1TTRMAPTAKR1C3CYP1A2
SCHEMBL28005064 0.84 FABP4 (0.56) PBRM1TTRMAPTAKR1C3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4064129-A Process for making quinacridone and its derivatives HARMON COLORS CORPORATION (US) 1977-12-20 US claimed
EP-1646691-B1 QUINACRIDONE PIGMENT COMPOSITIONS COMPRISING UNSYMMETRICALLY SUBSTITUTED COMPONENTS BASF SE (DE) 2014-06-25 EP disclosed
EP-2551304-A1 Quinacridone pigment compositions comprising unsymmetrically substituted components BASF SE (DE) 2013-01-30 EP disclosed
US-7166158-B2 Quinacridone pigment compositions comprising unsymmetrically substituted components CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-23 US disclosed
US-7166158-B2 Quinacridone pigment compositions comprising unsymmetrically substituted components CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-23 US disclosed
EP-1020497-B1 Mixed crystals of quinacridone pigments in the gamma phase CLARIANT GMBH (DE) 2004-03-17 EP disclosed
EP-0896034-B1 Mixed crystals of pigments on the basis of quinacridones CLARIANT GMBH (DE) 2002-05-08 EP disclosed
EP-0971001-B1 Process for the manufacture of quinacridone pigments CLARIANT GMBH (DE) 2002-01-02 EP disclosed
US-6312512-B1 POSSESS DEEPER HUES AND HAVE HIGH COLOR STRENGTHS; HIGHLY TRANSPARENT PIGMENTS WHICH ARE THEREFORE PARTICULARLY SUITABLE FOR THE PRODUCTION OF METALLIC PAINTS. CLARIANT GMBH (DE) 2001-11-06 US disclosed
EP-0799862-B1 Process for the manufacture of quinacridone pigments CLARIANT GMBH (DE) 2001-10-31 EP disclosed
US-6241814-B1 Process for preparing quinacridone pigments CLARIANT GMBH (DE) 2001-06-05 US disclosed
EP-1020497-A2 Mixed crystals of quinacridone pigments in the gamma phase Clariant GmbH (DE) 2000-07-19 EP disclosed
EP-0971001-A1 Process for the manufacture of quinacridone pigments Clariant GmbH (DE) 2000-01-12 EP disclosed
US-5989333-A RED-VIOLET PIGMENT COMPRISING BETA-PHASE QUINACRIDONE AND MINOR AMOUNT OF SUBSTITUTED QUINACRIDONE CRYSTALLIZED BY CYCLIZING CORRESPONDING DIANILINOTEREPHTHALIC ACIDS, HYDROLYZING THE MIXTURE UNDER PRESSURE, ISOLATING PIGMENT CLARIANT GMBH (DE) 1999-11-23 US disclosed
EP-0896034-A1 Mixed crystals of pigments on the basis of quinacridones Clariant GmbH (DE) 1999-02-10 EP disclosed
US-5755872-A HEATING, HYDROLYSIS, CYCLIZATION A DIANILINOTEREPHTHALIC ACIDWITH POLYPHOSPHORIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-26 US disclosed
EP-0799862-A2 Process for the manufacture of quinacridone pigments HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-08 EP disclosed
US-4124768-A Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids HOECHST AKTIENGESELLSCHAFT 1978-11-07 US disclosed