SCHEMBL6558610

SCHEMBL6558610

C=C(C)C(=O)Oc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.70
ALDH1A1 P00352 7/20 0.70
GAA P10253 5/20 0.70
HSP90AA1 P07900 1/20 0.70
ELANE P08246 1/20 0.64
POLB P06746 1/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
PTPN7 P35236 1/20 0.50
PTPN12 Q05209 1/20 0.50
ATM Q13315 1/20 0.48
GPR174 Q9BXC1 1/20 0.47
CASP3 P42574 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPK13 O15264 1/20 0.44
MAPK12 P53778 1/20 0.44
MAPK11 Q15759 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258850 0.93 MAPT (0.58) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL12258167 0.92 MAPT (0.59) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL22356340 0.90 MAPT (0.56) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL22258851 0.88 MAPT (0.53) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL11558754 0.87 MAPT (0.57) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL11553999 0.87 LMNA (0.52) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL13335351 0.85 ALDH1A1 (0.52) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL22356449 0.85 ALDH1A1 (0.51) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL15058 0.84 ELANE (0.73) MAPTALDH1A1GAAHSP90AA1ELANE
SCHEMBL87437 0.84 ELANE (0.73) MAPTALDH1A1GAAHSP90AA1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040097663-A1 Stabilising polymeric, organosilicon or silicone compositions RHODIA CHIMIE (FR) 2004-05-20 US claimed
EP-0787766-B2 Ambient vulcanising silicone rubbers crosslinking by condensation mechanism WACKER CHEMIE GMBH (DE) 2004-03-17 EP claimed
EP-0787766-B1 Ambient vulcanising silicone rubbers crosslinking by condensation mechanism WACKER CHEMIE GMBH (DE) 1999-08-04 EP claimed
US-3953411-A Age resistant polymers of 4-(arylamino)aryl esters of α,β unsaturated carboxylic acids THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-27 US claimed
US-20230136349-A1 CORE-SHELL DYE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2023-05-04 US disclosed
EP-2520972-B1 Liquid crystal display device alignment film, and method for manufacturing the same SAMSUNG DISPLAY CO LTD (KR) 2019-09-04 EP disclosed
US-6747079-B2 MERCAPTAN ESTER RHODIA CHIMIE (FR) 2004-06-08 US disclosed
US-20040097663-A1 Stabilising polymeric, organosilicon or silicone compositions RHODIA CHIMIE (FR) 2004-05-20 US disclosed
US-20030149170-A1 Method for stabilising silicone elastomer moulds RHODIA CHIMIE (FR) 2003-08-07 US disclosed
CN-1419583-A Method for stabilizing a mold made of a silicone elastomer RHODIA CHIMIE SA (FR) 2003-05-21 CN disclosed
US-6172150-B1 CONDENSATION-CROSSLINKING, ROOM-TEMPERATURE VULCANIZING SILICONE RUBBER HAVIN IMPROVED SERVICE LILFE WHEN USED AS FEMALE MOLD CONTAINS A MOLD-LIFE EXTENDING COMPONENT COMPRISING ONE OR MORE DIORGANO DITHIOPHOSPHATES WACKER-CHEMIE GMBH (DE) 2001-01-09 US disclosed
EP-0537640-B1 Polymers derived from a conjugated diolefin, a vinyl-substituted aromatic compound, and olefinically unsaturated nitrile GOODYEAR TIRE & RUBBER (US) 1996-12-18 EP disclosed
US-4559374-A VINYLIDENE CHLORIDE AND AT LEAST ONE MONO-ETHYLENTICALLY UNSATURATED CARBOXYLIC ACID THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-12-17 US disclosed
US-4480078-A MULTIZONAL POLYMERIZATION OF CONJUGATED DIENE, NONCARBOXYLIC COMONOMER, AND MALEIC OR ITACONIC ACID THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-30 US disclosed
US-4281080-A TACKIFIERS FOR RUBBERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-07-28 US disclosed
US-4147880-A Age resisters and age resistant polymeric compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-04-03 US disclosed
US-4147880-A Age resisters and age resistant polymeric compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-04-03 US disclosed
US-4010140-A Age resistant resin compositions and admixtures useful as adhesives THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US disclosed
US-3953411-A Age resistant polymers of 4-(arylamino)aryl esters of α,β unsaturated carboxylic acids THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-27 US disclosed
US-3953411-A Age resistant polymers of 4-(arylamino)aryl esters of α,β unsaturated carboxylic acids THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-27 US disclosed