Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558648 | 1.00 | TSHR (0.37) | TSHRALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL6559560 | 0.82 | ALDH1A1 (0.49) | TSHRALDH1A1KDM4EMAPTGAA | |
| SCHEMBL6560858 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6560861 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6558716 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6558711 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6561065 | 0.72 | MAPT (0.43) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6561063 | 0.72 | MAPT (0.43) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6558695 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL6558700 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |