Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920860 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL6558656 | 0.82 | TSHR (0.37) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL6558648 | 0.82 | TSHR (0.37) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL10444308 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL30888694 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL6559969 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL31393622 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL2320424 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10MAPK1MAPT | |
| SCHEMBL1569957 | 0.72 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10MAPTMAOB | |
| SCHEMBL29920457 | 0.72 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |