Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7830696 | 0.99 | TRPV1 (0.40) | TRPV1AKR1B1CFTRCYP3A4CNR1 | |
| SCHEMBL6558621 | 0.90 | TRPV1 (0.37) | TRPV1AKR1B1CNR1CNR2KCNA5 | |
| SCHEMBL7826422 | 0.84 | TRPV1 (0.39) | TRPV1AKR1B1CFTR | |
| SCHEMBL6560820 | 0.81 | KCNA5 (0.36) | TRPV1CFTRKCNA5 | |
| SCHEMBL6559484 | 0.81 | MAPT (0.36) | TRPV1KCNA5 | |
| SCHEMBL6559589 | 0.81 | TRPV1 (0.52) | TRPV1CFTRCYP3A4 | |
| SCHEMBL27520746 | 0.79 | TRPV1 (0.34) | TRPV1KCNA5 | |
| SCHEMBL6558599 | 0.78 | KDM4E (0.38) | TRPV1 | |
| SCHEMBL6558641 | 0.77 | TRPV1 (0.39) | TRPV1CYP3A4KCNA5 | |
| SCHEMBL6559509 | 0.76 | TRPV1 (0.45) | TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204134-C | Sulfamine-substituted benzodihydopyran, preparation method, use as medicine or diagnostic reagent and medicine containing same | HOECHST AG (DE) | 2005-06-01 | — | — | CN | disclosed |
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| CN-1169429-A | Sulfamine-substituted benzodihydopyran, preparation method, use as medicine or diagnostic reagent and medicine containing same | HOECHST AG (DE) | 1998-01-07 | — | — | CN | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |